The nutrients that trigger GLP-1 secretion are macronutrients – simple sugars (monosaccharides), peptides and amino acids (from proteins) and short chain fatty acids (from fats and also produced by good gut bacteria). GLP-1 is part of the signalling pathway that tells your body you have eaten, and prepare it to use the energy that comes from your food. Semaglutide works by mimicking the role of a natural hormone, called GLP-1 (glucagon like peptide-1) normally produced in response to detecting nutrients when we eat. Our body needs insulin to move the glucose (or blood sugar) we get from food inside cells, so we can use it as energy. Semaglutide also helps the pancreas produce insulin, which is how it helps manage type 2 diabetes.
This feeling of being satisfied or “full”, suppresses appetite. The active ingredient in Ozempic is semaglutide, which works by inducing satiety. Oscars host Jimmy Kimmel even joked about it on film’s night of nights last week.īut how much do we really need drugs like Ozempic? Can we use food as medicine to replace them? How does Ozempic work? A global supply shortage, tweets about using it from Elon Musk, approval for adolescent weight loss in the United States. Ozempic (and the similar drug Wegovy) has had more than its fair share of headlines and controversies. You’ve probably heard about the medication Ozempic, used to manage type 2 diabetes and as a weight loss drug.
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